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Ayoubkhani, D
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In a mouse MI model, the double knockout of HIF-1 and HIF-2 reduces macrophage glycolytic levels, leading to increased macrophage necrosis, impaired tissue fibrosis, and increased cardiac rupture in mice, suggesting that increased macrophage glycolysis post-MI is beneficial for their survival in hypoxic environments (229)
Br J Res
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