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Conversely, treatment of rats with the GIPR antagonist, rat GIP (330)NH2, does not modify food intake but significantly increases plasma TG and LPL compared with controls (Szalowska et al., 2011)
Side effects like nausea, vomiting, diarrhea, or constipation are common early on but often improve with proper management
Small steps like eating slowly, staying gently active, and listening to your body can make the process more comfortable
Additional research centered on making it a more druggable target with a longer half-life, and in 2005, a half-life of approximately 2.4 hours was achieved, which allowed for subcutaneous (SC) dosing twice a day
Some rely on extra coffee or energy drinks for a quick lift, but those fixes fade fast and can disrupt sleep
