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[31] Pregnancy registry data also suggest a possible association between the use of topiramate during pregnancy and congenital malformations such as craniofacial defects, hypospadias, and anomalies of various body systems

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Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression

[6] Its molecular structure could be idealized as HOOCCH(NH 2 )(CH 2 ) 2 COOH, with two carboxyl groups COOH and one amino group NH 2