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GLP-1 receptor agonists slow gastric emptying, meaning food remains in the stomach for longer periods before passing into the small intestine
In addition, GLP-1 increases the activity of protein kinase C (PKC) in islet cells in a dose-dependent manner, promotes pancreatic -cell survival, and inhibits mitochondria-dependent apoptosis by regulating Bcl-2/Bax expression levels (Zhang et al., 2015)
10.1007/s00535-011-0500-0 J
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