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While its role as a fatty acid transporter is its most famous biological function, recent biochemical research highlights that L-carnitine is also a vital cellular protector and metabolic buffer
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The anti-inflammatory effect produced by IL-10 is partly through a negative feedback loop with astrocytes, where the binding of IL-10 causes the release of TGF- from astrocytes, which subsequently attenuates pro-inflammatory cytokine production in primary microglia cells (Norden et al., 2014)
Interest in such applications is largely driven by their proposed mechanisms of action, including enhancement of tissue repair, modulation of inflammation, and cytoprotective effects observed in preclinical studies
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