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FDA cites potential immunogenicity for certain routes and complexities with peptide-related impurities and API characterization, and reports no or only limited safety information
This is particularly relevant given that mast cells are also located near neurons, glia, and cerebral blood vessels 20
Synphilin-1 associates with -synuclein and promotes the formation of cytosolic inclusions
Lyophilized (powder) -20C up to 2 years Reconstituted 2-8C up to 30 days
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