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In response to such stress, Nuclear factor erythroid 2-related factor 2 (NRF2) acts as a key transcription factor, coordinating multiple intracellular antioxidant defense systems by directly or indirectly regulating the expression of downstream target genes such as GPX4, thereby safeguarding cells from ferroptosis

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This is largely because our stomachs tend to produce less acid as we get older

Since vegetarians do not consume animal products, they are at a higher risk of developing B12 deficiency