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The addition of vitamins further enhances the serums ability to reduce the appearance of dark spots and improve overall skin clarity
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Representative drugs based on this mechanism include fomivirsen (Vitravene), mipomersen (Kynamro, Delisted), inotersen (Tegsedi), volanesorsen (Waylivra), and tofersen (Qalsody)
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FDA in 2010 for reducing excess visceral adipose tissue (VAT), the deep abdominal fat around the organs, in adults with HIV-associated lipodystrophy
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