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It is also sometimes used off-label for skin lightening, though evidence for this indication is limited

Final thoughts CagriSema represents the gold standard for medical weight loss peptide combinations - proven in Phase 3 trials to deliver 15-25% body weight loss through synergistic semaglutide and cagrilintide mechanisms

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Rapid dose escalation, lack of nutritional guidance, poor hydration, and limited symptom monitoring all increase risk

[22] [23] Evaluation should exclude other causes of liver disease, including viral hepatitis, alcohol-related liver disease, and medication-induced injury