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These include: Anaphylaxis : A severe, life-threatening allergic reaction that needs immediate help

after reconstitution, refrigerate at 28 C (35.646.4 F) and use within 24 weeks [4]

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Anti-tirzepatide antibodies were detected in 64.5% (1591/2467) of ZEPBOUND-treated patients in weight reduction clinical studies 1 and 2, and 60.6% (137/226) of ZEPBOUND-treated patients in OSA clinical studies [see Clinical Studies (14)]

Clinical guidance recommends testing before deciding on injections aimed at improving energy or weight