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A randomised trial found that patients who adhered to a low-calorie diet while on liraglutide lost significantly more weight than those who did not modify their diet, averaging an additional 3 kg over six months
Systemic effects of GLP-1 RAs, mediated via GLP-1 receptors in other organs and systems, include enhanced endothelial function and myocardial metabolism, natriuresis and anti-inflammatory and blood pressure-lowering effects
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Berg D, Borghammer P, Fereshtehnejad SM, Heinzel S, Horsager J, Schaeffer E, et al
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