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Overeating stretches your stomach lining in a way that triggers stronger nausea reflexes than it would have before starting treatment

71 As a result, endotoxins such as lipopolysaccharide (LPS) translocate across the epithelial barrier and reach the liver via the portal circulation

Animal studies have shown that even chronic daily exposure did not significantly desensitize GH release mechanisms [5] , though cycling is recommended as a precautionary measure