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Glutathione is synthesized in two sequential enzymatic reactions: glutamate cysteine ligase (GCL) catalyzes the first, rate-limiting step, and glutathione synthetase couples -glutamylcysteine to glycine in the last step [13]
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Inhibition of the GCL by buthionine sulfoximine (BSO) induces ferroptosis alone or enhances the sensitivity of cells to ferroptosis induced by other agents [32]
L-Theanine l g
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