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The following directions of activity are discussed in the preclinical literature: An important caveat: the mechanisms of DSIP are not fully resolved, and the body of evidence is inconsistent

How to evaluate the risks and benefits of medical interventions: procedural risks, complication rates, and asking informed questions [59:00]

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This overactivation causes an influx of calcium ions into neurons, which, in turn, activates calcium-dependent enzymes, such as calpain, nitric oxide synthase and phosphatase, resulting in the degradation of cytoskeletal proteins and damage to cell membranes