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The participants received weekly 2-milligram injections for six weeks, and the results were encouraging
Macrophage Death as a Pharmacological Target in Atherosclerosis
At 0.5mm, a stamped microneedle traverses the stratum corneum (typically 10 to 30 microns), passes through the viable epidermis (50 to 100 microns), and lands in the upper papillary dermis (which begins around 100 to 150 microns deep)
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For drugs with narrow therapeutic windows, this slowing of absorption can be clinically significant
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