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Of interest, treatment with TZT increases the expression of insulin-like growth factor (IGF) levels and associated binding proteins IGFBP1 and IGFBP2 (Thomas et al

However, there is limited experience in patients with severe hepatic impairment, and the medication should be used cautiously in this population

It may be reasonable to focus on whether the combination of GLP-1RAs and SGLT2is, which are expected to have complementary effects based on large-scale clinical trial results, can further reduce cardiovascular and renal events in patients with diabetes

Because it is found in high concentrations in the blood and muscle tissue, it acts as a versatile "workhorse" for various metabolic processes