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Finally, in 2023 the World Health Organization issued a guideline recommending against the use of non-sugar sweeteners for weight control or to reduce the risk of chronic disease, after a review found no long-term benefit for body fat and a possible association with type 2 diabetes and cardiovascular disease in long-term observational data
Arh Hig Rada Toksikol 72:157163
Chan, D
This is, of course, extremely unlikely to happen
Thus, it is likely that alterations of energy metabolism in schizophrenia represent a major contribution to changes in the levels of cerebral glutamate and glutamine (as well as N -acetylaspartate that is produced in mitochondria
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