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Liraglutide (Saxenda) earned FDA approval in 2014 to treat weight loss, but GLP-1s as a class took off with the 2021 approval of semaglutide (Wegovy) for chronic weight management
Stay hydrated Make sure to stay hydrated throughout the day
Fourth, an important issue that is often raised is whether any GLP-1RAs can indeed penetrate the bloodbrain barrier and therefore express any neurobiological activity in the CNS, which would result in cognitive or behavioral changes
The SELECT trial showed approximately 150 fewer MACE events per 10,000 person-years
I'm always skeptical of these kinds of things because at the end of the day, I think we can overthink it and again having balance, having the right level of macros
