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Consider Switching to a Non-Oral Method If youre starting a GLP-1 medication and long-term use is the plan, switching to a hormonal IUD, implant, or another non-oral option permanently simplifies the picture
And not surprisingly, some people are panicking
Understanding what each agent is and what it is not is essential before drawing any meaningful comparison
[31] Proportions of side effects were not noted in the phase 2 study, but results from an earlier phase 1 study, with 8 obese patients receiving weekly Mazdutide (9 mg) showed side effects of nausea (62.5% of patients), diarrhea (25%) and vomiting (37.5%) were seen after 12 weeks [32] , although it must be noted that these numbers probably deviate largely from the results in the phase 2 study, simply due to sheer differences in sample sizes
The practical difference between loading and not loading is 2-3 weeks of saturation time
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