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This resonates strongly with our recent European Heart Journal study (Baka et al., EHJ 2025), where metabolic modulation with SGLT2 inhibition improved energetic efficiency, contractile balance, and hypertrophy
The disadvantage is that small dosing errors become magnified
It pairs well with regular physical activity, dietary changes, and lifestyle adjustments
They are fundamental biological processes that operate across all vascularized tissue types
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