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The rats were euthanized, and tissue samples (brain, heart, kidneys, liver, spleen, lung, stomach, intestine, muscle, grease, ovaries, womb, testicles, and thymus) were collected at 3 min, 10 min, 1 h, and 24 h after administration (three males and three females at each time point)

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Vieira D, Gamarra L (2016) Getting into the brain: liposome-based strategies for effective drug delivery across the bloodbrain barrier

This approach falls outside the Summary of Product Characteristics (SmPC) dosing regimens and is not supported by UK guidance