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Side effects are rare at recommended doses, but long-term high doses may cause reversible sensory nerve damage (numbness, tingling), with dizziness and skin rash being uncommon
Plateaus may occur due to factors like diet, exercise routine, or individual metabolic rates
Another tumor suppressor, retinoblastoma (Rb), can directly regulate the glutamine transporter ASCT2 ( SLC1A5 ) to reduce glutamine uptake via the transcription factor E2F3 (Reynolds et al., 2014)
Mild symptoms such as nausea or fatigue may occur at first
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