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The strength of evidence depends on the specific application you're considering
Learn more about Tocopherol Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging
References Sikiric P, Seiwerth S, et al
The point is not to use those doses but to illustrate the wide safety margin
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