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Within two hours, he presented to the emergency department with: Diffuse body aches Blood pressure of 151/85 mmHg Heart rate of 130146 bpm Muscle tremors Elevated creatine phosphokinase (CPK) levels indicating muscle breakdown The patient developed rhabdomyolysis and renal dysfunction requiring ICU admission and aggressive fluid resuscitation with sodium bicarbonate

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Tirzepatide (Mounjaro, Zepbound) activates two: GLP-1 and GIP