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Roche's public obesity strategy, as of April 2026, centers on CT-388 (a GLP-1/GIP dual acquired through the Carmot Therapeutics acquisition) and a deep orforglipron-competitor oral GLP-1 program

Since its discovery, GLP-1 has emerged as an incretin hormone for its facilitation in insulin release and reduction of insulin resistance (IR)

Gagic D, Ciric M, Wen WX, Ng F, Rakonjac J

SeekPeptides members access detailed tracking tools and protocol guides that help evaluate whether any peptide therapy is producing meaningful results, including frameworks for deciding when to adjust, switch, or escalate treatment approaches

The agency emphasizes that compounded drugs do not undergo the same rigorous testing and approval process as FDA-approved medications, which means their safety and effectiveness are not guaranteed