Studies have shown that topiramate can reduce the waist-to-hip ratio, potentially helping with belly fat after 4 to 6 weeks of treatment
Singh, A., et al., Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis
Thats most likely because of the medication taking action in your body, and all the potential side effects that may come with it

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Presented for research literature review only Savushkina OK et al