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JAK, Janus Kinases
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The application of CRISPR/Cas9 technology on the targeted epigenome would be able to differentiate cell types to improve insulin production (Figure 3) that mitigate ROS without disrupting physiological redox signaling (Zaher and Stephens, 2025)
doi: 10.14814/phy2.14651 27 BiswasSCButeauJGreeneLA
A key mechanism involves their interaction with glial cells, as recent studies show that activated microglia and astrocytes can induce the expression of GLP-1 R, making them direct targets for GLP-1 mimetics [41]
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