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This matters for reading the evidence: a paper studying recombinant full-length T4 is not automatically evidence about a fragment sold as TB-500, and product labeling in the research-chemical channel is inconsistent enough that the exact contents of any given vial cannot be assumed
Researchers Rinky Kapoor et al
2012.DOI Pickart L., Vasquez-Soltero J., Margolina A
By dosage, the mean changes were: 500 mcg: 127% 750 mcg: 176% (single study) 1,000 mcg: 280% 1,500 mcg: 310% 2000 mcg: 260% 5,000 mcg: 62% While 1,500 mcg of vitamin B12 showed the highest average increase, the effect plateaued or declined at higher doses, suggesting a possible saturation of absorption pathways