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Conversely, those with severe gastroparesis, recent GLP-1 initiation, or polypharmacy involving multiple CYP3A4 inhibitors should obtain provider clearance before adding berberine
Mild side effects (water retention, injection-site reactions) may appear and typically resolve
Future studies including a broader age group and using specific behavioral assessments and scales are warranted
Thondam, S
10 , CD006423 (2011)
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