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Oral options may be better suited for patients who cannot tolerate injections, or as an adjunct to a broader protocol

Alcohol consumption while on tirzepatide compounds dehydration risk significantly

Fatigue reported by 15-20% of people

Due to the increased use of GLP-1 and GIP/GLP-1 receptor agonists in the treatment of T2DM and obesity, paired with increased inappropriate prescribing for weight loss, drug manufactures are simply unable to maintain a supply that is sufficient to meet this increased demand

Patients taking medications for conditions such as epilepsy or those who are on antipsychotic therapy should also exercise caution