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For the remaining seven drugs (Phenylbutazone, Meropenem, Diethylstilbestrol, Prazosin, Enoxacin, Glipizide, and Doripenem), dose responses and heat maps summarizing the dose-response results for the glutathione and senescence assays are presented in Fig
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It has potent effects of antioxidant, anti-inflammatory, anti-angiogenesis, and anti-cancer [131]
Radical is an intermediate species with high chemical activity produced during cellular metabolism, can attack protein, DNA and lipid macromolecule in cell membrane, and damage the physiological function of these macromolecules, making the cell membranes lose their function and shorten the life of cells
& Langer, T
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