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This can lead to decreased activities of pyruvate dehydrogenase and key TCA cycle enzymes, potentially causing an imbalance between OXPHOS and cellular energy demands
10.1002/hipo.10220 52 ClaassenJ
Because these regulators coordinate transcriptional activity across multiple downstream targets, their perturbation can influence precursor allocation, branch competition, and stress-responsive signaling
Plant Foods, Antioxidant Biomarkers, and the Risk of Cardiovascular Disease, Cancer, and Mortality: A Review of the Evidence
By employing a -adrenergic receptor blocker and a ghrelin receptor antagonist, they discovered that the oral intake of hydrogen water activates the -adrenergic receptor signaling pathway in the stomach, inducing ghrelin secretion, which in turn protects dopaminergic neurons in MPTP-induced PD model mice
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