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The effect occurs because GLP-1 slows carbohydrate absorption and enhances insulin release only when blood glucose rises, avoiding dangerous low-blood-sugar episodes
These reports vary
Long-term use of GLP-1 medications may be necessary for some patients as they work to lose weight and maintain their results over time
Notably, these drugs are currently not covered for weight loss in Medicare, due to a long-time exclusion of treatment for weight loss
Over time, however, clinical guidelines have expanded their role significantly
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