This study was supported by the Shandong University of Traditional Chinese Medicine Doctoral Student Quality Improvement Innovation Project (YJSTZCX2024018), the Inheritance Studio of Traditional Chinese Medicine Master Zhang Canjia of State Administration of Traditional Chinese Medicine (no.(2010) 59), the Chinese Medicine Science and Technology Project of Shandong Province in 2023 (M-2023031), and the Key Project of Undergraduate Teaching Reform Research in Shandong Province (Z2023292)
Ma N, Zhang Z, Liao F, Jiang T, Tu Y
Le TB-500 (a fragment of thymosin beta-4) primarily acts on cell migration and actin regulation
Researchers have also examined its effects on gut epithelial and endothelial models in the context of gastrointestinal barrier research (Sikiric et al., 2025, Pharmaceuticals)
Mechanisms of action studied in research Scientific publications, notably those by Pickart et al., describe several mechanisms of interest: Gene expression modulation transcriptomic studies have shown that GHK-Cu influences the expression of several thousand human genes, particularly those involved in tissue repair