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Healthcare providers and patients can report suspected adverse reactions to the FDA MedWatch program
From an immunological perspective, these associations arise from a breakdown in self-tolerance mediated by overlapping T-cell and B-cell autoreactivity, shared cytokine pathways (e.g., IFN-, IL-18), and common antigen-presenting HLA alleles
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For example, adding 1mL more to an existing 2mL reconstitution gives you 3mL total, yielding a 3.33mg/mL concentration
