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Originally designed as a treatment for type II diabetes, in 2021, the FDA approved Semaglutide to be used as a weight loss treatment
In head-to-head studies, injectable semaglutide produces greater weight reduction than the 14 mg oral dose
There is no evidence that split dosing produces better outcomes when the once-weekly protocol is already effective
Coverage may require prior authorization, lab results, diagnosis details, or proof that other medications were tried first
For non-diabetic patients whose insurance denies coverage entirely, the cash-pay options are the same as for everyone else: NovoCare ($149 to $349/month), LillyDirect ($299 to $449/month), or patient assistance programs if income-eligible
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