The conditions that have been associated with glutathione deficiency include the following: Neurodegenerative diseases such as Alzheimers, Parkinsons and Huntingtons disease and ALS Pulmonary diseases such as COPD, asthma, and acute respiratory distress syndrome Immune system disorders Cardiovascular diseases such as high blood pressure, elevated cholesterol, and heart attacks Chronic age-related disorders such as cataracts, macular degeneration, hearing impairment, and glaucoma Liver disease Cystic fibrosis Aging processes (Pizzorno, 2014)
The depletion of GSH is necessary for the progression of apoptosis that is mediated by various signaling pathways (3,4)
If you added 1.5mL instead of 2mL, your concentration is 5mg divided by 1.5mL equals 3.33mg/mL
Some individuals have reported contact sensitization so be sure to patch test if you have reactive or sensitive skin
mEPSC events were detected using the software MiniAnalysis (Synaptosoft, Decatur, GA, USA) with a 5 pA amplitude threshold and all mEPSCs were verified visually