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Our structure identified an unpredicted non-peptide agonist-binding pocket in which reorganization of extracellular loop 3 and transmembrane helices 6 and 7 manifests independently of direct ligand interaction within the deep transmembrane domain pocket
SREBP-1c and lipogenesis in the liver: an update1
DOI: Published online: November 8, 2021 1 Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea 2 Asan Diabetes Center, Asan Medical Center, Seoul, Korea 3 Department of Internal Medicine, H Plus Yangji Hospital, Seoul, Korea Corresponding author: Woo Je Lee Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea E-mail: [email protected] *Hwi Seung Kim and Taekwan Yoon contributed equally to this study as first authors
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