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In a longitudinal study of such patients, mean pro-C3 increased with worsening of fibrosis and decreased with fibrosis improvement 36
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65 ) (Addgene, 52961) for CRISPRCas9 KO or into pLV hU6-sgRNA hUbC-dCas9-KRAB-T2a-Puro 66 (Addgene, 71236) for CRISPRi knockdown, as previously described 41
Available at: ninds.nih.gov/funding/research/ parkinsonsweb/drug_summaries
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