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TB-500, a synthetic version of the naturally occurring Thymosin Beta-4 peptide fragment, appears to promote cell migration, differentiation, and wound healing by regulating actin polymerization and increasing vascular endothelial growth factor (VEGF) activity

2013 Dec;21(6):1612-6

In connective tissue and cell research, the compound has been studied for collagen turnover and collagen fibers

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A growing body of evidence reveals pervasive iron homeostasis disruption and elevated lipid peroxidation in the cartilage, subchondral bone, and synovial tissue of OA patients, correlating positively with disease severity and cartilage damage