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Glossary TMI traumatic muscle injury MRI magnetic resonance imaging IL interleukin TNF- tumor necrosis factor- TGF- transforming growth factor- CD8+ T cells cluster of differentiation 8 positive T cells IFN- interferon- MCP monocyte chemoattractant protein Tregs regulatory T cells M1 pro-inflammatory macrophage M2 anti-inflammatory macrophage CXCL C-X-C motif chemokine ligand NETs neutrophil extracellular traps ROS reactive oxygen species NAF neutrophil-activating factor HMGB1 high-mobility group box 1 protein ADA adenosine deaminase CK creatine kinase MDA malondialdehyde NF-B nuclear factor kappa-light-chain-enhancer of activated B cells MAPK mitogen-activated protein kinase STAT signal transducer and activator of transcription VEGF vascular endothelial growth factor NSAIDs non-steroidal anti-inflammatory drugs CAR-Tregs chimeric antigen receptor-r T cells EMBASE excerpta medica database GFEMs glycoprotein 130-expressing macrophages PPAR/RXR peroxisome proliferator-activated receptor gamma/retinoid X receptor TKO triple knockout EGFR epidermal growth factor receptor GDF-15 growth differentiation factor FAPs fibro adipogenic progenitors RIZs regenerative inflammatory regions ST suppression of tumorigenicity MMP-8 matrix metalloproteinase-8 SOD-2 superoxide dismutase 2 GPX glutathione peroxidase CAT catalase TRX thioredoxin TLRs toll-like receptors DAMPs damage-associated molecular patterns ERK extracellular signal-regulated kinase c-Jun N-terminal kinase JNK MPO myeloperoxidase PI3K phosphoinositide 3-kinase Akt protein kinase B mTOR mammalian target of rapamycin STAT1 signal transducer and activator of transcription 1 JAK1 janus kinase 1 NO nitric oxide PKC protein kinase C NAMPT nicotinamide phosphoribosyl transferase GM-CSF granulocyte-macrophage colony-stimulating factor IgE immunoglobulin E COX cyclooxygenase ELF-EMF extremely low-frequency electromagnetic fields

Alcohol consumption can potentially negatively impact both parts of your immune system, as it disrupts the inflammation signals your body relies upon to distinguish whether it's healthy

10.1016/J.BBAGEN.2014.11.021 106 KovacsG