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This definitive review synthesizes the extensive preclinical evidence on BPC-157s dual action on gastrointestinal repair and neuroprotection, providing a clear framework for understanding its role as a master BPC-157 gut-brain axis modulator

Established pharmacological options including acamprosate, naltrexone, and nalmefene remain the evidence-based first-line treatments

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Oncotarget 5 , 47224731 (2014)

A closer look at the data The study, sponsored by Novo Nordisk , and co-led by Professor Newsome at the Roger Williams Institute of Liver Studies and Dr Arun Sanyal at Virginia Commonwealth University, evaluated 800 participants with biopsy-confirmed MASH who received either weekly semaglutide injections or placebo for 72 weeks