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On one hand, it is reassuring that the episodes were mostly transient and clustered during the step-up from 2.4 to 7.2 mg
MOTS-c is widely referenced in metabolic and aging research literature for its characterized role in cellular stress response, AMPK pathway activation, and glucose and lipid metabolism regulation in experimental models
Heres why I still use it often in my practice at JourneyLite: 1
Pharmacologically this yields a highly selective GHS-R1a agonist which, in classical rodent studies (Raun et al., Eur J Endocrinol 1998), does not significantly elevate cortisolemia, ACTH, prolactin or FSH/LH at effective doses, unlike GHRP-2 and GHRP-6
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