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The expense of these medications can impact patient access and adherence
You should not take metformin if you have severe kidney disease
Oral GLP-1 programs remained minimal until the late 2000s, then began rising meaningfully post-2018with the most visible step-up in the last few years: 10 oral programs in 2022, and 11 each in 2024 and 2025
No safety data exists for this population
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