This was achieved by activating retinal GLP-1 R and inhibiting the overexpression of placental growth factor (PLGF) and intercellular adhesion molecule-1 (ICAM-1), thereby stabilizing tight junction proteins and preserving BRB integrity
But the same trial flagged more atrial fibrillation, more blood clots, and, in a follow-up, more broken bones, most of them from ordinary falls, for reasons nobody has fully explained (New England Journal of Medicine, 2024)
GLP-1 weight loss injections are considered safe for most individuals when used under the supervision of a healthcare provider
Capsules go through the digestive system first
Tsurusaki S, Tsuchiya Y, Koumura T, et al