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The result is weight regain leading to the recurrence of pre-diabetes, hypertension, dyslipidemia, and other risks , and essentially wasted effort, cost, and time

Published in Cell Metabolism in July 2024 and written by Qingwen Qian and colleagues, it described a novel mechanism by which activation of the integrated stress response pathway, known as endoplasmic reticulum (ER) stress, in the hypothalamus is induced by obesity-related inflammation, Abel says

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But we cant ignore our thyroid in this approach either because, as with almost everything within our bodies, theres a feedback loop between our various body parts and the chemical messages they produce

Yehuda, S., & Carasso, R