For one, rapid weight loss (whether from medication, diet, or other lifestyle habits) is known to temporarily disrupt hormonal levels
Delgado CA, Balbueno Guerreiro GB, Diaz Jacques CE, de Moura Coelho D, Siita A, Manfredini V, Wajner M, Vargas CR (2019) Prevention by L-carnitine of DNA damage induced by 3-hydroxy-3-methylglutaric and 3-methylglutaric acids and experimental evidence of lipid and DNA damage in patients with 3-hydroxy-3-methylglutaric aciduria
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We included all new adult patients ( 18 years) with a recorded BMI 27 kg/m 2 and no diagnosis of type 1 or type 2 diabetes mellitus