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A 2022 analysis published in JASN (Journal of the American Society of Nephrology) examining GLP-1 receptor agonist use in patients with CKD stages 2 to 4 found a favorable renal safety profile overall, but emphasized the importance of hydration counseling during dose escalation [10]

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This does not mean, of course, that there is no need for caution, and clinical research is continuing to investigate these potential effects of GLP-1 use