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In isolated rat aorta preparations, the peptide produced concentration-dependent vasodilation that was endothelium-dependent and abolished by L-NAME, and co-immunoprecipitation work traced the response to phosphorylation of Src, caveolin-1, and endothelial nitric oxide synthase, with reduced binding between caveolin-1 and eNOS [1]

Whats new is the price, says Graham Simpson, M.D., a physician with Opt Health, a telemedicine clinic that offers peptides

It is also quite reasonably priced