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A wide assortment of modulators has been used and validated

Methionine also has antioxidant properties, and it encourages the creation of new proteins within cells

Some protocols involve continuous administration for 6-12 months with periodic assessment and dose adjustment

Magnetic resonance spectroscopy (MRS) allows the insight into their pathophysiology through exploration of a range of biochemicals putatively relevant to aetiological processes, in particular mitochondrial dysfunction and energy metabolism